Evaluation of New Pentamethoxy Flavonol 'Cordiofolinol'
as Anti-Inflammatory Principle from Haldina cordifolia Bark Extract
A novel Pentamethoxy Flavonol 'Cordiofolinol' (P3) has been isolated from anti-inflammatory activity guided fractionation of methanol extract of Haldina cordifolia stem Bark with a gradient of methanol in chloroform. Further P3 was screened for anti-inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P3 has showed significant reduction in inflammation caused by carrageenan (P>0.01) and dextran (P>0.05). Hence P3 can be considered as the principle component responsable for the anti-inflammatory activity for Haldina cordifolia bark.…
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Produktdetails
Weitere Autoren: Lal Khosa, Ratan / Parcha, Versha
- ISBN: 978-3-8443-8730-8
- EAN: 9783844387308
- Produktnummer: 37678950
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2011
- Seitenangabe: 84 S.
- Masse: H22.0 cm x B15.0 cm x D0.5 cm 143 g
- Abbildungen: Paperback
- Gewicht: 143
Über den Autor
Dr. Vichitra Kaushik currently working as Associate Prof in M.M.College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India, Dr. R L Khosa, formerly Prof and HOD Pharmacy, IT, BHU, India, Currently Director (P&D) Pharmacy, BIT, Meerut, India and Dr. Versha Parcha as Prof in DOPS, S.B.S.P.G.I., Dehradun, UK, India.
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