Swati Gupta
EGFR Targeted Gemcitabine PLGA Nanoparticles for Pancreatic Cancer
Buch
Adenocarcinoma of the exocrine pancreas is the fourth leading cause of cancer deaths in the United States. Currently, surgery is the only treatment, although due to its late presentation, only 9% to 15% of patients are suitable for surgery. The median survival for all stages of pancreatic cancer is 3 to 5 months from diagnosis. The underlying problem in the use of anticancer drugs is their toxicity and poor bioavailability. It is expected that if a delivery system-bearing anticancer drugs can be delivered in a targeted fashion, inhibition of tumor growth with reduced systemic toxicity will occur. The book describes the preparation and charact…
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Beschreibung
Adenocarcinoma of the exocrine pancreas is the fourth leading cause of cancer deaths in the United States. Currently, surgery is the only treatment, although due to its late presentation, only 9% to 15% of patients are suitable for surgery. The median survival for all stages of pancreatic cancer is 3 to 5 months from diagnosis. The underlying problem in the use of anticancer drugs is their toxicity and poor bioavailability. It is expected that if a delivery system-bearing anticancer drugs can be delivered in a targeted fashion, inhibition of tumor growth with reduced systemic toxicity will occur. The book describes the preparation and characterization of anti EGFR monoclonal antibody conjugated Gemcitabine loaded PLGA nanoparticles for their selective delivery to pancreatic cells and evaluation of the systems in vitro.
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Produktdetails
Weitere Autoren: Aggarwal, Sahil
- ISBN: 978-3-659-76831-6
- EAN: 9783659768316
- Produktnummer: 37404793
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2015
- Seitenangabe: 140 S.
- Masse: H22.0 cm x B15.0 cm x D0.8 cm 227 g
- Abbildungen: Paperback
- Gewicht: 227
Über den Autor
Swati Gupta (M.Pharm, Ph.D), has nearly thirteen years of research experience. She has supervised 15 M.Pharm students and supervising Ph.D students. Dr Gupta has been awarded with BOYSCAST fellowship and Bio-CARe women scientist award from Ministry of Science and Technology, New Delhi. Dr Gupta has over forty five publications to her credit.
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