Sanjay Patel
Drug Eluting Stents
Drug Eluting Stents: Existing Era and New Concerns
Buch
Interventional cardiologists have quickly replaced bare metal stents with intravascular drug-eluting stents (DES) for treating and preventing restenosis, largely on the basis of empirical evidence that shows profound reduction in angiographic and clinical restenosis. A critical reassessment of the published evidence, however, suggests that the putative superiority of intravascular drug-eluting stents is founded on questionable premises, including overestimation of restenosis benefit, underestimation of the risk for stent thrombosis, overreliance on soft rather than hard outcomes and the attendant overestimation of cost-effectiveness. Because…
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Beschreibung
Interventional cardiologists have quickly replaced bare metal stents with intravascular drug-eluting stents (DES) for treating and preventing restenosis, largely on the basis of empirical evidence that shows profound reduction in angiographic and clinical restenosis. A critical reassessment of the published evidence, however, suggests that the putative superiority of intravascular drug-eluting stents is founded on questionable premises, including overestimation of restenosis benefit, underestimation of the risk for stent thrombosis, overreliance on soft rather than hard outcomes and the attendant overestimation of cost-effectiveness. Because the long-term incremental risks, benefits, and costs of drug-eluting stents have not yet been optimally evaluated in a broad spectrum of patient and lesion cohorts, the rational role of these devices in clinical management warrants reappraisal. This book will provide a brief overview of the development of drug-eluting stents from the laboratory bench to their investigation in clinical trials and their clinical use.
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Produktdetails
Weitere Autoren: Patel, Maulik
- ISBN: 978-3-659-19582-2
- EAN: 9783659195822
- Produktnummer: 37771249
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2012
- Seitenangabe: 124 S.
- Masse: H22.0 cm x B15.0 cm x D0.7 cm 203 g
- Abbildungen: Paperback
- Gewicht: 203
Über den Autor
Dr. Sanjay S. Patel, working as an Associate Professor in Pharmaceutical Technology Department since 2006 and Mr Maulik J. Patel working as an Assistant Professor in Pharmaceutical Technology at Department Shri B. M. Shah College of Pharmaceutical Education and Research, Modasa - 383315, India
22 weitere Werke von Sanjay Patel:
Drug Eluting Stents: Existing Era and New Concerns
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