Narinder Singh
Development of Isoniazid Loaded Silk Fibroin Microsphere
Development of Microsphere for Antitubercular Drug
Buch
Current experimental investigation is dedicated to prepare microspheres with small size and good Sphericity by Phase Separation method using Isoniazid (INH) as model drug. Silk fibroin has unique intrinsic qualities like biodegradability, biocompatibility or release properties and their tunable drug loading capacity. The delivery loading proficiency of the drug molecules in silk spheres be contingent on their charge and hydrophobicity or subsequent in altered drug release profile. In the present work Isoniazid loaded silk fibroin microsphere was prepared by using phase Separation method. Microsphere was evaluated by Ultraviolet-visible spectr…
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Beschreibung
Current experimental investigation is dedicated to prepare microspheres with small size and good Sphericity by Phase Separation method using Isoniazid (INH) as model drug. Silk fibroin has unique intrinsic qualities like biodegradability, biocompatibility or release properties and their tunable drug loading capacity. The delivery loading proficiency of the drug molecules in silk spheres be contingent on their charge and hydrophobicity or subsequent in altered drug release profile. In the present work Isoniazid loaded silk fibroin microsphere was prepared by using phase Separation method. Microsphere was evaluated by Ultraviolet-visible spectroscopy, Fourier Transform Infrared spectroscopy, Entrapment efficiency, Scanning electron microscopy Studies. Scanning electron microscopy studies revealed that Isoniazid Loaded Silk Fibroin Microspheres were spherical. Experimental report disclosed a new aqueous based formulation method for silk spheres with controllable shape or size and sphere. Isoniazid loaded silk microspheres may act as ideal nanoformulation with elaborated studies.
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Produktdetails
Weitere Autoren: Gautam, Surya Prakash / Kaur, Rajinderpal
- ISBN: 978-3-330-05767-8
- EAN: 9783330057678
- Produktnummer: 37542815
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2017
- Seitenangabe: 92 S.
- Masse: H22.0 cm x B15.0 cm x D0.6 cm 155 g
- Abbildungen: Paperback
- Gewicht: 155
Über den Autor
Narinder Singh (M.Pharma) (Pharmaceutics) from CT Institute of Pharmaceutical Sciences, Jalandhar, Punjab with first division & (B.Pharma) from Rayat-Bahra Institute of Pharmacy, Hoshiarpur, Punjab. Author has presence in the pharmaceutics research.Have authored research/review publications.Author has grateful to Parents & Dr. Surya Prakash Gautam.
26 weitere Werke von Narinder Singh:
Development of Microsphere for Antitubercular Drug
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Development of Microsphere for Antitubercular Drug
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