Design selective glutamate dehydrogenase inhibitors?
To what extent is it possible to
Plasmodium falciparum glutamate dehydrogenase (GDH) is an attractive target for the rational development of new antimalarial drugs. Enzyme Kinetics assays and molecular modelling technology were used to measure inhibition effects for some ligands on two different GDHs. The study presented in this work provided a base line for future explorations and discoveries of the inhibition selectivity between Plasmodium and human GDH based on bacterial and mammalian animal GDH.
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Produktdetails
- ISBN: 978-3-8443-0158-8
- EAN: 9783844301588
- Produktnummer: 37825094
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2011
- Seitenangabe: 132 S.
- Masse: H22.0 cm x B15.0 cm x D0.8 cm 215 g
- Abbildungen: Paperback
- Gewicht: 215
Über den Autor
Yunbo Song got the B.Medicine degree at School of Dentistry,Peking University in China and M.Sc. degree at National University of Ireland in 2005,where the research project in this book was carried out by him. Following that he pursues a Ph.D degree in Neuroscience program at University at Buffalo in USA, which is expected to be achieved in 2011.
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