Chymotrypsin Inhibitors:N-substituted sulfamoylacetamides
N-substituted sulfamoylacetamides derived from 4-acetamidobenzenesulfonyl chloride as Chymotrypsin Inhibitors
A facile method has been implemented for the synthesis of different N-substituted sulfamoylacetamides (3a-q) by the reaction of 4-acetamidobenzenesulfonyl chloride with a series of different alkyl/aralkyl/aryl amines in aqueous alkaline media under dynamic control of pH at 9-10. The structures of the synthesized N-substituted sulfamoylacetamides were elucidated through spectral analysis like FT-IR, EIMS and 1H-NMR. The synthesized derivatives were further screened against Chymotrypsin enzyme. The results revealed that most of the synthesized compounds were found to be potent chymotrypsin inhibitor.
CHF 52.90
Preise inkl. MwSt. und Versandkosten (Portofrei ab CHF 40.00)
V105:
Folgt in ca. 15 Arbeitstagen
Produktdetails
Weitere Autoren: Shafique, Maryam
- ISBN: 978-3-659-64891-5
- EAN: 9783659648915
- Produktnummer: 37428211
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2014
- Seitenangabe: 72 S.
- Masse: H22.0 cm x B15.0 cm x D0.4 cm 125 g
- Abbildungen: Paperback
- Gewicht: 125
Über den Autor
Sabahat Zahra Siddiqui is serving as Lecturer in the Department of Chemistry, GC University-Lahore and has authored more than 40 research publications. She worked as a research scholar at University of Pennsylvania, USA under IRSIP-HEC scholarship.
5 weitere Werke von Sabahat Zahra Siddiqui:
Bewertungen
Anmelden