Cell Polarity and Subcellular RNA Localization
Selective cytoplasmic organelle and protein targeting has long been thought to constitute the sole determinant of cell polarity and complexity. This view has been changed, however, by the discovery of differential subcellular RNA distribution patterns. Over the past decade it has become clear that selective mRNA sorting and translation contributes to an accumulation of cognate proteins at discrete cellular sites. In this book, various systems are discussed (e.g. Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activ…
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Produktdetails
- ISBN: 978-3-540-40025-7
- EAN: 9783540400257
- Produktnummer: 37193344
- Verlag: Springer Berlin Heidelberg
- Sprache: Englisch
- Erscheinungsjahr: 2012
- Seitenangabe: 221 S.
- Plattform: PDF
- Auflage: 2001
- Reihenbandnummer: 34
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