Cancer Cell Signaling & Small Molecule Inhibitors
Target based approach in combating cancer
Cancer is the prime root of death worldwide, thereby, unsurprisingly causing the figure of deaths to increase evidently. Surprisingly, colorectal carcinoma is the third most frequently diagnosed cancer and also the third foremost cause of death in men and women globally. The accumulation of genetic and epigenetic alterations facilitates colorectal cancer (CRC) formation by deregulating key signaling pathways in cancer cells. The principal role of phosphoinositide-3-kinase (PI3K) activation in tumor cell biology has encouraged a considerable effort to target PI3K and/or downstream effectors such as Akt, mTOR and FoxO3a in colorectal carcinoma.…
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Produktdetails
- ISBN: 978-613-4-90072-0
- EAN: 9786134900720
- Produktnummer: 37485043
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2018
- Seitenangabe: 248 S.
- Masse: H22.0 cm x B15.0 cm x D1.5 cm 387 g
- Abbildungen: Paperback
- Gewicht: 387
Über den Autor
Dr. Asif K Qazi, MSc., Biochemistry, Kashmir University, India. PhD, Biochemistry, Jamia Hamdard, India. Post Doctorate, UNMC, USA. Currently, Senior Resident at SKIMS, India. He contributed in the area of Cancer cell signaling and Cancer drug discovery and credited Patents, Book chapters and 22 Research articles in reputed International Journals.
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