Calcium Entry Blockers in Cardiovascular and Cerebral Dysfunctions
2 The free internal Ca+ concentration in human red cells is set according to the leak 2 and-pump principle: There is a finite passive Ca+ influx at the physiological 2 2 Ca+ -gradient across the membrane which is compensated by Ca+ pumping in the outward direction with a rate given by the degree of saturation of the A TP-fuelled Ca 2 pump at the steady-state internal Ca+ concentration. Simons (1982) recently devised a method allowing the measurement of the steady 2 2 state internal Ca+ concentration. Cells are suspended in media of different Ca+ con 2 2 tent whose Ca+ concentration is monitored by a Ca+ -selective electrode. When the cell…
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Produktdetails
Weitere Autoren: Herman, A. G. (Hrsg.) / Wellens, D. (Hrsg.)
- ISBN: 978-94-009-6033-6
- EAN: 9789400960336
- Produktnummer: 37249030
- Verlag: Springer Netherlands
- Sprache: Englisch
- Erscheinungsjahr: 2012
- Seitenangabe: 325 S.
- Plattform: PDF
- Auflage: 1984
- Reihenbandnummer: 40
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