Biological study of Schiff Base Metal Complexes derived from Drugs
The work presented concerns the preparation, characterization and biological evaluation of Cu(II) and Zn(II) complexes of Schiff bases derived from amoxycillin, cephalexin, sulphamethoxazole and trimethoprim, and salicylalde-hyde and pyridoxal. In these complexes an amino group available in the drug substances was allowed to react with salicylaldehyde and pyridoxal hydrochloride, separately, to obtain Schiff bases which were, subsequently, reacted with Cu(CH3COO)2. H2O and/or Zn(CH3COO)2.2H2O to form Schiff base metal complexes. The ligands and the complexes were characterized by microanalytical, thermogravimetric, magnetic and spectroscopic…
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Produktdetails
Weitere Autoren: Arif, Muhammad / Iqbal, Mohammad Saeed
- ISBN: 978-3-659-45946-7
- EAN: 9783659459467
- Produktnummer: 37715836
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2014
- Seitenangabe: 200 S.
- Masse: H22.0 cm x B15.0 cm x D1.2 cm 316 g
- Abbildungen: Paperback
- Gewicht: 316
Über den Autor
Dr. Iftikhar H. Bukhari is working as Professor & Chairperson, Department of Chemistry, Government College University, Faisalabad, Pakistan. 28 years teaching and research experience. More than 75 National & International research publications. Field of Specialization is Bioinorganic Chemistry. Research interest in Metal Catalyzed reactions.
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