Antihyperglycemic Activity of Oxazolidine Derivatives
Importance of oxazolidine
The number compounds have been prepared in order to improve the pharmacological pro¿les of antihyperglycemic activity. The series of 3-benzyl-2-(4'-substituted phenyl)-4(5H)-(4''-nitrophenyl amino)-1, 3-oxazolidines 6a-e were tested against hyperglycemic activity. Their antihyperglycemic activity was evaluated by Streptozotocin (STZ) and Sucrose-loaded (SLM) model. The results of studies indicate that the compounds 6a, b, c, d, e displayed signi¿cant reduction in blood glucose level in streptozotocin and sucrose loaded rat models. The purity of the synthesized compounds was characterized by means of IR, 1H-NMR, mass spectral and elemental ana…
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Produktdetails
- ISBN: 978-3-659-44810-2
- EAN: 9783659448102
- Produktnummer: 37413568
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2013
- Seitenangabe: 68 S.
- Masse: H22.0 cm x B15.0 cm x D0.4 cm 119 g
- Abbildungen: Paperback
- Gewicht: 119
Über den Autor
Dr. Theivendren Panneer Selvam M.Pharm., Ph.D Assistant ProfessorPES's Rajaram and Tarabai Bandekar College of PharmacyFaramagudi, Ponda, Goa, INDIAResearch Area: Design, Synthesis, Characterization, Molecular Modeling and Biological Screening of Novel Heterocyclic Derivatives.
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