An Efficient Pyrimidine Scaffolds against Bacterial Strains
Pyrimidine Derivatives
A series of novel 2-(substituted benzylidene)-7-(4-bromophenyl)-5-(furan-2-yl)-2H-thiazolo[3,2-a]pyrimidin-3(7H)-ones were synthesized by using established methods and were characterized by IR, 1H NMR and Mass spectroscopy in order to confirm their formation. These compounds were synthesized to evaluate their antitubercular, antibacterial and antifungal potency. Docking studies revealed the importance of functional groups and its different biological action. They were found to be potent against Mycobacterium tuberculosis H37Ra strain, also potent against Gram +ve, Gram -ve and fungal strains
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Produktdetails
Weitere Autoren: D. Phadte, Vijaysarathy / Valzita, Silveira Karyn
- ISBN: 978-3-659-42851-7
- EAN: 9783659428517
- Produktnummer: 37418177
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2013
- Seitenangabe: 168 S.
- Masse: H22.0 cm x B15.0 cm x D1.0 cm 268 g
- Abbildungen: Paperback
- Gewicht: 268
Über den Autor
Dr. Theivendren Panneer Selvam M.Pharm., Ph.D Assistant ProfessorPES's Rajaram and Tarabai Bandekar College of PharmacyFaramagudi, Ponda, Goa, INDIAProf.K.R.S.Sambasiva Rao, Ph.D., DSc. Acharya Nagarjuna University, Guntur, A.P., INDIA Prof.Bhaskara R. Jasti, Ph.D. ChairmanUniversity of Pacific, Stockton, CA
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