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Joel (Hrsg.) Barrish

Accounts in Drug Discovery: Case Studies in Medicinal Chemistry

Buch

Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome. The Editors cover a wide range of therapeutic areas and medicinal chemistry strategies, including lead optimization starting from high-throughput screening hits as well as rational, structure-based design. The chapters include follow-ons and next generation compounds that aim to improve upon first-generation agents. This volume surveys the range of challenges commonly faced by medicinal chemistry researchers, including the optimization of metaboli… Mehr

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Produktdetails


Weitere Autoren: Carter, Percy (Hrsg.) / Cheng, Peter (Hrsg.)
  • ISBN: 978-1-84973-126-3
  • EAN: 9781849731263
  • Produktnummer: 8257906
  • Verlag: Royal Society Of Chemistry
  • Sprache: Englisch
  • Erscheinungsjahr: 2010
  • Seitenangabe: 370 S.
  • Masse: H24.2 cm x B16.4 cm x D2.7 cm 712 g
  • Reihenbandnummer: 4
  • Gewicht: 712

Über den Autor


Joel C. Barrish was awarded his Ph.D. in Organic Chemistry from Columbia University; spent 25 years as a medicinal chemist in Drug Discovery Research; co-inventor of the anti-cancer agent SPRYCEL and is currently Vice President in Discovery Chemistry responsible for multiple programs across therapeutic areas. Percy H. Carter was awarded his Ph.D. in Organic Chemistry from Harvard University; 10 years as a medicinal chemist in Drug Discovery Research and is currently Group Director in Discovery Chemistry responsible for multiple programs Inflammation Research. Peter T. W. Cheng was awarded Ph.D. in Organic Chemistry from the University of Toronto; approximately 20 yrs as a medicinal chemist in Drug Discovery Research and is currently a Research Fellow in Metabolic Diseases Chemistry. Robert Zahler gained his Ph.D. in Organic Chemistry from the California Institute of Technology; approximately 30 yrs experience as a medicinal chemist in Drug Discovery Research and is the inventor of the anti-infective agent Entecavir.

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