Muhammad Athar Abbasi

5-substituted-1,3,4-oxadiazole-2-thiols

Synthetic 5-substituted-1,3,4-oxadiazole-2-thiols derivatives as viable therapeutic entrants for Alzheimer's Disease

Buch

In the present work, Different substituted derivatives of 5-substituted-1,3,4-oxadiazole-2-thiols were synthesized by successive conversions of 5-substituted carboxylic acids into respective ester, hydrazide and 1,3,4-oxadiazole. Finally the target compounds were obtained by reaction of 5-substituted-1,3,4-oxadiazole-2-thiols with a series of various electrophiles,in N,N-dimethyl formamide (DMF) in the presence of sodium hydride (NaH)which acts as a base. The structural characterization of these newly synthesized compounds was done by IR, 1H-NMR and EI-MS spectral data. All these compounds were evaluated for their enzyme inhibitory potentials… Mehr

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Produktdetails

Weitere Autoren: Siddiqui, Sabahat Zahra

ISBN: 978-3-659-59528-8
EAN: 9783659595288
Produktnummer: 37429994
Verlag: LAP Lambert Academic Publishing
Sprache: Englisch
Erscheinungsjahr: 2014
Seitenangabe: 84 S.
Masse: H22.0 cm x B15.0 cm x D0.5 cm 143 g
Abbildungen: Paperback
Gewicht: 143

Über den Autor

Muhammad Athar Abbasi (Assoc. Prof., GCU, Lahore) is HEC approved supervisor. He is a recipient of Research Productivity Award from 2008-14 from PCST, Pakistan. He has authored 141 research papers.Sabahat Zahra Siddiqui (Lecturer, GCU, Lahore) has authored 40 research publications. She worked as a research scholar at University of Pennsylvania.